Alright, so one piece of art I had no issue compressing and it wasn't blurry. This second one I've done gets really blurry when I compress it. Does anyone have any suggestions on how to keep it from getting blurry on me?

How are you compressing it? I use the save for web option in photoshop and it usually spits out decent quality. Also make sure your starting resolution is 72 dpi.

I wasn't actually having an issue apparently. Apparently my web browser is funky on my laptop and i need to zoom out to 80% or all pictures are kind of fuzzy and i never really noticed